Healthy Blood Pressure Protocol - Healthy Blood Pressure Protocol |
| 2019-06-03 09:05:04 by clara
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Recently with enhanced scientific advancement and understanding, a much clearer picture is emerging. At the center of this new understanding is a transcription factor called nuclear factor (erythroid-derived 2)-like 2, or Nrf2. High levels of free radicals turn on Nrf2 which is a protein that is dormant until it is activated by a Nrf2 activator.
Once released Nrf2 migrates into the cell nucleus where it binds to the DNA at the location of the Antioxidant Response Element (ARE). The transcription factor Nrf2 binds to the ARE. Activation of this pathway drives expression of antioxidant enzymes. The mechanism of Nrf2 activation involves a protein named Keap1, a suppressor protein anchored in the cytoplasm that physically binds Nrf2. Activation of Nrf2 essentially opens the door for the cell to produce a vast array of important antioxidants.
As it turns out a variety of foods such as turmeric, green tea extract as well as coffee act are powerful activators of the Nrf2 pathway. While not necessarily rich in antioxidants in themselves, they directly enable and amplify the cell's innate ability to produce vast antioxidant protection by signaling the DNA. In this way, specific molecules from Nrf2 activating foods can trigger the production of thousands of antioxidant molecules, providing far better protection against the damaging effects of free radicals compared to standard antioxidant supplements.
Nrf2 fine-tunes the expression of hundreds of genes, including the familiar antioxidant enzymes in addition to a large numbers of genes that control seemingly dissimilar processes such as immune versus inflammatory responses, tissue remodeling versus fibrosis, carcinogenesis versus metastasis, and even cognitive dysfunction versus addictive behavior.https://dietsheriff.com/healthy-blood-pressure-protocol-review/ |
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